microsatelliteinstabilityimmunotherapy

由 IH Sahin 著作 · 2022 · 被引用 18 次 — Immunotherapy—particularly immune checkpoint inhibitor therapy—has revolutionized the management of several solid tumors, leading to rapid ...

由 QX Wang 著作 · 2021 · 被引用 17 次 — The degree of microsatellite instability predicts response to PD-1 blockade immunotherapy in mismatch repair-deficient/microsatellite ...

由 P Zhao 著作 · 2019 · 被引用 477 次 — Several clinical trials have demonstrated that mismatch repair deficiency or microsatellite instability-high is significantly associated with ...

由 C Luchini 著作 · 2019 · 被引用 733 次 — ESMO recommendations on microsatellite instability testing for immunotherapy in cancer, and its relationship with PD-1/PD-L1 expression and tumour ...

由 E Alouani 著作 · 2023 · 被引用 4 次 — Metastatic colorectal cancers (mCRCs) with mismatch repair deficiency (MMRd)/microsatellite instability (MSI) exhibit poor prognosis and may be ...

2023年3月6日 — Immunotherapy increases the body's ability to identify and attack these cells, and cancers that have high microsatellite instability actually ...

由 J Ros 著作 · 2023 · 被引用 5 次 — Microsatellite instability (MSI) is a biological condition associated with inflamed tumors, high tumor mutational burden (TMB), and responses to immune ...

由 R Motta 著作 · 2021 · 被引用 37 次 — If the tumor shows high MSI (MSI-H), immunotherapy is the treatment of choice. If the aim of therapy is to achieve a high response rate and the ...

由 R Cohen 著作 · 2019 · 被引用 32 次 — Microsatellite instability (MSI) is a molecular indicator of defective DNA mismatch repair (dMMR) and is observed in approximately 5% of metastatic ...